About

Differential Gene Set Enrichment Analysis (DGSEA) is an adaptation of the original Gene Set Enrichment Analysis algorithm from the Broad Institute / MIT. It is a computational method that determines whether two a priori sets of genes show statistically significant differences between two biological states.

Detailed methodology can be found in our manuscript, which is at Bioinformatics.

DGSEA was a collaboration between the labs of Nicholas Graham (USC) and William Lowry (UCLA) and was executed by James Joly. This work was supported by the Viterbi School of Engineering (USC), the Mork Family Department of Chemical Engineering and Materials Science (USC), and the National Institute of Health (NIAMS).